Acute Disseminated Encephalomyelitis (ADEM)

Table of Contents

  1. Disorder
  2. Epidemiology
  3. Pathophysiology
  4. Risk Factors & Associations
  5. Signs & Symptoms
  6. Diagnostic Criteria
  7. Diagnostic Workup
  8. Disease Modifying Therapy (DMT)
  9. Non-DMT Treatment
  10. Followup
  11. Scales
  12. Prognosis
  13. References

Pathophysiology

Risk factors & Associations

Signs & Symptoms

Diagnostic Criteria

Diagnostic Workup

  • Median age of onset: 40 years
  • Sex Distribution: 
    • Seropositive (Anti-AQP4 positive): 90% female
    • Seronegative (Anti-AQP4 negative): Equal sex distribution
  • Genetics: Up to 3% of cases are familial

Disease Modifying Therapy (DMT)

Disorder

A rare autoimmune disease that affects the central nervous system

Epidemiology

Non-DMT Therapies

Followup

Scales

Prognosis

References